KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
21.21
Human Site:
Y696
Identified Species:
42.42
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
Y696
P
Q
S
S
T
M
G
Y
M
G
S
Q
S
V
S
Chimpanzee
Pan troglodytes
XP_511742
777
85768
Y696
P
Q
S
S
T
M
G
Y
M
G
S
Q
S
V
S
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
Y696
P
Q
S
S
T
M
G
Y
M
G
S
Q
S
V
S
Dog
Lupus familis
XP_540486
782
86005
Y700
P
Q
S
S
A
M
G
Y
M
G
S
Q
S
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
Y694
P
Q
T
S
N
I
G
Y
M
G
S
Q
P
M
S
Rat
Rattus norvegicus
Q9JJ50
776
86228
Y695
P
Q
T
S
N
I
G
Y
M
G
S
Q
P
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
Q673
G
M
G
Y
M
G
A
Q
S
V
P
M
T
Y
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
G667
Q
Q
P
Q
Q
I
P
G
Q
Q
P
Q
Q
I
P
Honey Bee
Apis mellifera
XP_393989
830
92147
P671
P
T
A
V
H
M
P
P
H
Q
G
P
Q
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
P693
Q
Q
Q
Q
Q
P
P
P
P
P
Q
Q
Q
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
E551
D
E
E
S
S
T
Q
E
S
R
E
R
P
Y
P
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
Q653
V
Q
P
S
Q
T
P
Q
Q
A
H
Q
R
V
P
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
26.6
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
0
0
0
0
9
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
0
0
9
50
9
0
50
9
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
25
0
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
9
0
0
9
42
0
0
50
0
0
9
0
17
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
59
0
17
0
0
9
34
17
9
9
17
9
25
0
25
% P
% Gln:
17
75
9
17
25
0
9
17
17
17
9
75
25
9
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% R
% Ser:
0
0
34
67
9
0
0
0
17
0
50
0
34
0
50
% S
% Thr:
0
9
17
0
25
17
0
0
0
0
0
0
9
0
9
% T
% Val:
9
0
0
9
0
0
0
0
0
9
0
0
0
42
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
50
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _